SAFETY INDEX OF ULTRA-SHORT ACTING INTRAVENOUS ANAESTHETICS

Thiazolodiazepines: New Ultra-short Acting Hypnotics

The synthesis and hypnotic evaluation of a new generation of thiazolo[3,2-a][1,3]diazepine analogs are described. Those compounds exhibit potent in vivo activities as ultra-short acting hypnotics. Background of the Invention Surgical procedures require the administration of several intravenous drugs to ensure hypnosis, analgesia, relaxation and control of visceral reflex responses. The use of i...

Thiazolodiazepines: New Ultra-short Acting Hypnotics

The synthesis and hypnotic evaluation of a new generation of thiazolo[3,2-a][1,3]diazepine analogs are described. Those compounds exhibit potent in vivo activities as ultra-short acting hypnotics. Background of the Invention Surgical procedures require the administration of several intravenous drugs to ensure hypnosis, analgesia, relaxation and control of visceral reflex responses. The use of i...

Intravenous infusion of ultra-short-acting β-blocker for postoperative atrial fibrillation is the one of choice.

ostoperative atrial fibrillation (POAF) develops during the early phase in 20–40% of patients undergoing cardiac surgery.1,2 Its incidence depends on the type of surgery, the patient’s age, history of atrial fibrillation, left ventricular function, arterial hypertension, chronic obstructive pulmonary disease, history of heart failure and so on. POAF may affect the length of hospital stay and pr...

pain management in intensive care unit patients: the role of ultra-short acting opioid: remifentanil

Randomized Study on the Efficacy and Safety of Landiolol, an Ultra-Short-Acting β1-Adrenergic Blocker, in Patients With Acute

s a treatment for acute myocardial infarction (AMI), thrombolytic therapy was started in the early 1980 s,1 and now the best strategy is reperfusion of the occluded coronary artery and restoration of coronary blood flow with percutaneous coronary intervention (PCI) early after the onset of AMI.2 Despite the fact that the outcome of AMI has improved with the reperfusion strategy, morbidity and m...